Amany Abdel-Motaleb, M.S., MB(ASCP)CM
Lead Consultant, Biomedical Laboratory and Molecular Diagnostics
Molecular Biologist | Clinical Laboratory Operations | Assay Development
MicroFab Design and Consulting, LLC | microfab-consulting.com
Professional Profile
ASCP-certified molecular biologist and laboratory operations leader with more than 10 years of experience in molecular diagnostics, assay development, clinical laboratory startup, academic instruction, and biotechnology research. Expertise includes NGS, PCR/qPCR, RNA-Seq, CAP/CLIA/NYSDOH-regulated testing, quality systems, LIMS implementation, and cross-functional team leadership. Built and launched a CLIA-compliant NGS laboratory and authored peer-reviewed research in molecular diagnostics, microbiology, nanotechnology, and cancer genomics.
Core Consulting Services
- Biomedical laboratory planning and startup, including workflow design, equipment and inventory planning, SOP development, LIMS implementation, and operational readiness.
- Molecular assay and workflow development for NGS, PCR/qPCR, RNA-Seq, and high-complexity clinical testing.
- Clinical laboratory quality systems and regulatory-readiness support involving CAP, CLIA, and NYSDOH requirements.
- Biomedical product support, scientific assessment, technology evaluation, and biology-to-engineering integration.
I. Professional Experience
Lead Consultant | MicroFab Design and Consulting, LLC
- Advises on biomedical laboratory planning and launch, molecular assay and workflow development, clinical laboratory startup, quality systems, and LIMS implementation.
- Supports biomedical products and scientific assessments and helps integrate biological requirements with engineering development activities.
Adjunct Faculty | University of St. Francis
- Taught multiple sections of undergraduate biology laboratories, emphasizing scientific methodology, laboratory safety, and hands-on experimentation.
- Developed laboratory activities, assessments, and student-support strategies aligned with course objectives.
Clinical Laboratory Supervisor | Belay Diagnostics
- Built a clinical NGS laboratory from inception, overseeing procurement, workflow development, SOP creation, and regulatory compliance.
- Directed laboratory operations, quality systems, technology evaluation, inventory management, and LIMS implementation.
- Led troubleshooting, corrective actions, budgeting support, and continuous process-improvement initiatives.
- Collaborated with the Finance Controller, Medical Director, and Senior Vice President of Operations to prepare annual laboratory budget proposals, including staffing requirements and equipment upgrades.
Senior Molecular Technologist | Belay Diagnostics
- Developed a novel assay to detect and characterize glioblastoma from cerebrospinal fluid in collaboration with Johns Hopkins.
- Performed and interpreted high-complexity molecular diagnostic testing using advanced sequencing technologies, including the NovaSeq X Plus.
- Trained six molecular biology technologists; procured and managed laboratory inventory and equipment; and supported assay optimization and quality initiatives.
Data Analyst and Data Management Specialist | Sema4
- Analyzed up to 300 clinical laboratory datasets daily and generated operational, productivity, and quality reports using LIMS and Excel-based tools.
- Collaborated with laboratory leadership and quality teams to improve workflow efficiency and identify process issues before implementation.
Clinical Laboratory Technologist II | Sema4
- Performed up to 200 high-complexity molecular tests daily and supported assay development for hereditary cancer and carrier-screening programs using varied specimen types in CAP-, CLIA-, and NYSDOH-regulated environments.
- Maintained regulatory compliance while developing SOPs, training materials, and workflow improvements.
- Partnered with laboratory leadership to support priority clinical cases and laboratory process optimization.
Teaching Assistant | The American University in Cairo
- Supported undergraduate biology laboratory instruction, tutoring, grading, and laboratory-safety initiatives.
Research Assistant | The American University in Cairo
- Conducted interdisciplinary research in microbiology, molecular biology, nanotechnology, and analytical chemistry focused on rapid detection of foodborne pathogens.
- Created and optimized bacterial-detection methods using FTIR spectroscopy, magnetic and gold nanoparticles, PCR, and modified DNA-extraction protocols.
- Managed experimental design, laboratory procurement, data analysis, manuscript preparation, and scientific reporting, resulting in peer-reviewed publications and conference presentations.
Embryology Laboratory Technologist | Dr. Faris Medical Center
- Performed diagnostic semen analysis and evaluated male-fertility specimens using established laboratory protocols and sterile techniques.
- Conducted cryopreservation and storage of reproductive specimens in liquid nitrogen, ensuring specimen integrity and accurate documentation.
- Examined testicular biopsy and epididymal aspiration samples for diagnostic and assisted reproductive technology applications, including in vitro fertilization.
- Prepared embryo-culture dishes, laboratory reagents, and supporting materials while maintaining quality standards and patient confidentiality.
II. Education
M.S., Biotechnology | The American University in Cairo
Concentrations: Genetic Regulatory Networks, Bioinformatics, and RNA-Seq Analysis.
B.S., Biology | Northern Illinois University
Concentrations: Cell and Molecular Biology, Human Biology, and Biochemistry.
III. Certification
Molecular Biology, MB(ASCP)CM | American Society for Clinical Pathology
IV. Peer-Reviewed Publications
- “Fast Detection of Bacterial Contamination in Fresh Produce Using FTIR and Spectral Classification.” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, September 2021.
- “Toward Colorectal Cancer Biomarkers: The Role of Genetic Variation, Wnt Pathway, and Long Noncoding RNAs.” OMICS: A Journal of Integrative Biology, April 2021.
- “Detection of Acinetobacter baumannii in Fresh Produce Using Modified Magnetic Nanoparticles and PCR.” Analytical Chemistry, August 2020.
V. Technical Skills
- Molecular Diagnostics and Genomics: NGS, cancer genomics, assay development, PCR/qPCR, RNA-Seq, DNA/RNA extraction, capillary electrophoresis, and DNA-fragmentation assays.
- Laboratory Techniques: Cell and tissue culture, flow cytometry, mass spectrometry, FTIR, UV-visible spectroscopy, nanoparticle synthesis, and microbiology.
- Laboratory Operations: CLIA and CAP environments, quality systems, SOP development, LIMS, laboratory startup, inventory management, staff training, and process improvement.
- Data and Reporting: Clinical laboratory data analysis, Excel-based reporting, scientific writing, manuscript preparation, and cross-functional communication.